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Wolverine peptide vial
Recovery Peptides

Wolverine

BPC-157 + TB-500 Recovery Stack

Provider-guided peptide stack for eligible patients focused on recovery support. Whether the Wolverine stack is appropriate for you is determined during a licensed-provider evaluation; outcomes are individual and not guaranteed.

From $189/mo

Monthly (Cancel Anytime)  |  3-Month & 6-Month Bundles Available

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Frequency

As Prescribed

Rx Required

Yes — Prescribed Online

Pharmacy

US-Registered

Shipping

Free & Discreet

Mechanism

How the Wolverine Stack Works

The Wolverine Stack combines BPC-157 (Body Protection Compound-157) and TB-500 (a synthetic analog of thymosin beta-4), two peptides studied in preclinical research for complementary cellular-signaling activity.

BPC-157 is a gastric-derived peptide that has been studied in preclinical models for its activity on growth-factor expression in fibroblasts, angiogenesis (formation of new blood vessels), collagen synthesis, and inflammatory cytokine pathways including TNF-alpha and IL-6. Research has examined its activity in models of muscle, tendon, ligament, and gut-barrier biology.

TB-500 is studied in preclinical research for its activity on cell migration, actin cytoskeleton remodeling, angiogenesis, and tissue elasticity, with research examining markers of fibrotic-scar reduction and collagen architecture. Clinical applicability in humans is determined by a licensed provider during evaluation; individual outcomes vary.

Benefits

What the Wolverine Stack Can Do for You

Recovery-Focused Treatment Plans

May be considered as part of a personalized recovery plan developed with your licensed provider, who evaluates your medical history, goals, and eligibility.

Cellular Signaling Research

Both peptides have been studied in preclinical research for activity on cellular signaling pathways. Specific relevance to your goals is evaluated by your provider during evaluation.

Recovery Support Research

Studied in preclinical research for potential effects on fibroblast migration, collagen synthesis, and angiogenesis. Clinical application is determined by your provider during evaluation.

Joint Biology Research

Studied in preclinical research for activity on cellular signaling in joint and connective-tissue biology. Patient-reported experiences vary; your provider sets realistic expectations during evaluation.

Gastrointestinal Wellness Discussion

Topics discussed with your provider during medical evaluation. Specific gastrointestinal concerns require a separate medical assessment.

Local + Systemic

BPC-157 and TB-500 have been studied in research for complementary activity on cellular signaling. Eligibility and any personalized plan are determined by a licensed provider during evaluation.

Composition

Active Ingredients

BPC-157 (Body Protection Compound) TB-500 (Thymosin Beta-4)
Your Journey

What to Expect

1

Week 1-2: Initial Plan Phase

Patient-reported timelines vary. Your provider will discuss realistic expectations during follow-up; outcomes are individual and not guaranteed.

2

Week 2-4: Provider Check-In

Many patients meet with their provider to review progress and adjust their regimen as needed.

3

Week 4-8+: Ongoing Provider Follow-Up

Patients continue working with their provider to evaluate response and refine their plan based on individual goals.

Compounding Notice

Wolverine is a compounded peptide blend (BPC-157 + TB-500) that is not approved by the U.S. Food and Drug Administration (FDA). It is prepared by a U.S.-registered compounding pharmacy for individual patients based on a valid prescription, and its components are classified by the FDA as bulk drug substances under section 503A of the Federal Food, Drug, and Cosmetic Act. Use only under the ongoing supervision of a licensed healthcare provider. Learn more about compounded medications under section 503A.

Important Safety Information

The Wolverine Stack (BPC-157 + TB-500) is not FDA-approved. It is compounded by a US-registered pharmacy under physician supervision. Side effects are generally rare and mild, and may include minor injection site irritation or temporary dizziness.

BPC-157 and TB-500 have been studied extensively in preclinical settings with strong safety profiles. Not recommended during pregnancy or breastfeeding. Consult your healthcare provider to determine if this therapy is appropriate for you.

Ready to take the next step?

Complete a brief online evaluation to see if the Wolverine Stack is right for you. A licensed provider will review your health profile and create a personalized plan.

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FAQ

Wolverine questions, answered

Wolverine is a compounded peptide combination of BPC-157 (Body Protection Compound) and TB-500 (Thymosin Beta-4 fragment), available through Madison Meds for eligible patients as part of a provider-guided recovery plan. The specific role is determined during a licensed-provider evaluation.
BPC-157 is a 15-amino-acid synthetic peptide derived from a protective protein found in human gastric juice. It has been studied in animal models for effects on tendon, ligament, muscle, and gut tissue, primarily through proposed mechanisms involving angiogenesis and growth factor expression (Sikiric et al., Current Pharmaceutical Design, 2010 and subsequent reviews). Human clinical trial data is more limited, but the safety profile in available research is favorable.
TB-500 is a synthetic fragment of Thymosin Beta-4 (TB4), a naturally occurring peptide. In preclinical research it has been studied for activity on cellular signaling pathways, including cell migration and vascular formation (Goldstein et al., 2012, Ann. N.Y. Acad. Sci.). Clinical applicability in humans is a determination made by a licensed provider during evaluation.
BPC-157 and TB-500 act on overlapping but distinct cellular signaling pathways and have been studied in preclinical research for potentially complementary mechanisms. Clinical applicability in humans is a determination made by a licensed provider during evaluation; outcomes are individual and not guaranteed.
The Wolverine peptide combination is discussed with eligible patients during a licensed-provider evaluation. Whether it is appropriate is a clinical determination based on your medical history and wellness goals; outcomes vary and are not guaranteed.
When prescribed, Wolverine is administered as a subcutaneous injection in the abdomen. Frequency and duration are personalized by the prescribing provider. Detailed instructions and supplies are included with each shipment from the dispensing pharmacy.
Patient-reported timelines vary considerably. Your provider will set realistic expectations during evaluation; results are individual and not guaranteed.
Both BPC-157 and TB-500 have favorable safety profiles in preclinical research and anecdotal human use, with side effects rare and typically mild — temporary injection-site irritation, occasional fatigue, or mild flu-like symptoms in the first few days. Large-scale human clinical trials are limited; your Madison Meds provider screens for contraindications and discusses risks before prescribing.
Both BPC-157 and TB-500 are not FDA-approved as finished medications, but can be prescribed and compounded by US-licensed pharmacies under section 503A of the Federal Food, Drug, and Cosmetic Act. Madison Meds works exclusively with US-licensed compounding pharmacies that source pharmaceutical-grade peptides from FDA-registered facilities. Patients should not purchase peptides from non-licensed sources, which carry significant safety and quality risks.
Through Madison Meds, Wolverine (BPC-157 + TB-500 stack) is available starting at $189/month after a licensed provider evaluation, with the medications dispensed by a US-licensed compounding pharmacy. Pricing is bundled to include the provider consultation, medication, and free discreet shipping. Concierge recovery clinics commonly charge $400–$800+ for a comparable stack; the cash-pay model removes the markup.

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